Oncotarget Published Study Reveals What Antibiotics Do to Cancer Cells

Could cancer be treated with conventional antibiotics? In a study, published on Oncotarget, researchers introduce a new scenario to treat the disease. Together with British colleagues, and researchers from New York and Philadelphia, scientists have tested five different antibiotics on cancerous cell lines from eight different tumor types.

The five antibiotics used were Azithromycin, Doxycycline, Tigecycline, Pyrvinium Pamoate, and Chloramphenicol. Four of these antibiotics destroyed the cancer stem cells in each test. This was true for glioblastoma, the most aggressive form of a brain tumor, as well as cancers of the lung, prostate, breast, and skin. Researchers believe the reason the antibiotics may be as effective on these cells is because of the negative impact on the mitochondria. Oncotarget is also available on Dove Press.

According to the researchers, these cancerous cell components are also referred to as the power plants of cells. They supply energy needed by cancer stem cells, for example in order to grow and divide, allowing tumors to grow. One explanation is that mitochondria are derived from bacteria. Therefore, these antibiotics can be used against that bacteria. Lead researcher, Professor Michael P. Lisanti says he was aware of the impact antibiotics had on the mitochondria, and the significance for tumor growth. He believes if the connection between antibiotics and the eradication of cancer stem cells are confirmed, we could be using this strategy soon, which would make anti-cancer drugs more affordable.

Oncotarget researchers were brought together from the Manchester Cancer Research Centre, National Cancer Institute, National Institutes of Health, Breakthrough Breast Cancer, with funding from the University of Manchester and ERC Advanced Grant. The report was published on Oncotarget, a respected peer-reviewed online journal that focuses on Oncology topics.

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Each year, thousands of research reports are published on Oncotarget, and when it comes to oncology journals, they rank number one. This free access to scientific findings help maximize visibility by offering a wide distribution of information to colleagues and the public.

Lifeline Screening Can Make The Difference Between Good Health And Bad

There are many ailments that tend to go unnoticed by us as we trek throughout our lives, yet manifest as “sudden” ailments later on. If we are smart, we would have periodic checkups from time to time from our doctor, but sadly most of us don’t take advantage of that availability.

Many such bodily ailments can be discovered early on by a process called screening. In a variety of ways, medical experts can perform a screening and discover what actions can be taken to preserve our health.

Lifeline screening provides several forms of tests that can be given without going to a doctor’s office or a hospital to have them done. These are routine scans that are given at discounted prices that will do basic health scans on equipment not usually found in a doctor’s office, but in hospitals and testing facilities.

Lifeline Screening provides tests using three basic technologies. One is ultrasound, a second is finger-stick blood screenings, and the third is a limited electrocardiograph.

The are similar to when a mother gets a screening for a new baby in the womb. Sound waves are sent out, and the image of the internal organs show up on the screen in real time. This type of test can show if blood vessels are blocked, such as the carotid arteries or the abdominal aortic vessel to test for an aneurysm. The Ankle-brachial index screening can be performed to test for peripheral arterial disease as well as a test for bone density to test for osteoporosis.

The finger-stick blood test can give a complete lipid blood panel, as well as a glucose screening to check for blood sugar levels, a CRP screening for cardiovascular disease and elevated liver enzymes.

A limited cardiograph tests for atrial fibrillation, which is an irregular heartbeat, also called A-fib. This can be serious, yet it can go unnoticed by an individual.

All the results of the screenings can be made available to a person’s doctor for evaluation.